Ciprofloxacin 500mg – 50tablets (5 packs of 10 tablets)
Broad-spectrum antimicrobial agent of fluoroquinolone group. It has a bactericidal effect. Inhibits DNA gyrase and inhibits bacterial DNA synthesis.
Highly active against most gram-negative bacteria: Pseudomonas aeruginosa, Haemophilus influenzae, Escherichia coli, Shigella spp., Salmonella spp., Neisseria meningitidis, Neisseria gonorrhoeae.
Active against Staphylococcus spp. (including strains producing and not producing penicillinase, methicillin-resistant strains), some strains of Enterococcus spp., Campylobacter spp., Legionella spp., Mycoplasma spp., Chlamydia spp., Mycobacterium spp.
Ciprofloxacin is active against β-lactamase producing bacteria.
To ciprofloxacin resistant Ureaplasma urealyticum, Clostridium difficile, Nocardia asteroids. The action on Treponema pallidum is not well understood.
Rapidly absorbed from the gastrointestinal tract. Bioavailability after oral administration is 70%. Eating has little effect on the absorption of ciprofloxacin. Plasma protein binding is 20-40%. It is distributed in tissues and body fluids. Penetrates into the cerebrospinal fluid: concentrations of ciprofloxacin in non-inflammatory meninges reach 10%, in inflamed – up to 37%. High concentrations are achieved in bile. It is excreted in the urine and bile.
Infectious and inflammatory diseases caused by microorganisms sensitive to ciprofloxacin, including diseases of the respiratory tract, abdominal cavity and pelvic organs, bones, joints, skin; septicemia; severe infections of ENT organs. Treatment of postoperative infections. Prevention and treatment of infections in patients with reduced immunity.
For topical use: acute and subacute conjunctivitis, blepharoconjunctivitis, blepharitis, bacterial corneal ulcers, keratitis, keratoconjunctivitis, chronic dacryocystitis, meibomitis. Infections of the eye after injury or contact with foreign bodies Preoperative prophylaxis in ophthalmic surgery.
Individual. Inside-250-750 mg 2 times / day. Duration of treatment – from 7-10 days to 4 weeks.
For on / in a single dose-200-400 mg, the multiplicity of administration – 2 times / day; duration of treatment – 1-2 weeks, if necessary, and more. Can be administered in/in a jet, but preferably drip for 30 minutes.
When applied topically instilled 1-2 drops into the lower conjunctival SAC of the affected eye every 1-4 hours After improvement, the interval between instillations can be increased.
The maximum daily dose for adults when administered is 1.5 g.